Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

catalog :

FC00193

quantity :

100Âµg, 500Âµg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

OKT10

reactivity :

human

application :

flow cytometry

product information

sku :

FC00193

status :

Enabled

name :

Anti-human CD38 Monoclonal Antibody Unconjugated, Flow Validated

category name :

Primary Antibodies, Monoclonal Antibodies, Flow Cytometry Antibodies

gene name :

CD38

price various sizes :

100ug / $79 500ug / $320 25 tests / $79

clonality :

Monoclonal

clone number :

OKT10

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

PBS, pH7.2, 0.09% NaN3

description :

Monoclonal clone# G2 antibody for CD38 detection. Host: Mouse.Size: 100Âµg, 500Âµg. Tested applications: Flow Cytometry. Reactive species: Human. CD38 information: Molecular Weight: 34328 MW; Subcellular Localization: Membrane; Single-pass type II membrane protein; Tissue Specificity: Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.

short description :

Mouse Monoclonal Anti-human CD38 Unconjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

description1 :

Introduction . CD38 is a type II transmembrane glycoprotein of 45 kDa with a protein core of 35 kDa. The CD38 antigen is expressed on essentially all pre-B lymphocytes, plasma cells, and thymocytes. It is also present on activated T lymphocytes, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. The antigen is expressed during the early stages of T- and B-lymphocyte differentiation, is lost during the intermediate stages of maturation, and then reappears during the final stages of maturation. The CD38 antigen is expressed on 90% of CD34+ cells, and is not expressed on pluripotent stem cells. Coexpression of CD38 antigen on CD34+ cells indicates lineage commitment of those cells. CD38 is a counter-receptor of CD31. It is also expressed in T- and B-acute lymphoblastic leukemia (ALL), Burkitts lymphoma, multiple myeloma, acute myeloid leukemia (AML), and chronic lymphocytic leukemia (CLL). The OKT10 antibody directed against human CD38 antigen. . This antibody is routinely tested by flow cytometric analysis. Flow cytometry and other applications were tested during antibody development by CapricoBio or are reported in the literature. Application Information . Each lot of this antibody has been quality control tested by flow cytometric analysis of human PBMCs. For flow cytometric staining, the recommended use of this antibody is 0.5ug per 1x106 cells in 100ul of staining volume or 0.1ml whole blood followed by a secondary florescent conjugated anti-mouse antibody. However, it is strongly suggested that the antibody reactivity be empirically titrated for optimal performance in the application of interest.

size :

100Âµg, 500Âµg

uniprot id :

P28907

host :

Mouse

form :

Liquid

purification :

Protein A purified

storage :

4 C . Do not freeze.

isotype :

IgG1, k

sensitivity :

5ul per sample

application details :

User need to optimize the dilution ratio for this antibody

applications :

Flow Cytometry

reactivity :

Human

image labels :

Lymphocytes gated PBMCs stained with purified anti-human CD38 (clone OKT-10) followed by Goat anti-mouse IgG (H+L) Alexa Fluor 488 (red histogram). PBMCs monocytes stained with only Goat antimouse IgG (H+L) Alexa Fluor 488 (Blue histogram).

competitor equivalent skus :

sc 15362 sc 374650 sc 7049 sc 51726 sc 7048 sc 18858 sc 7047 sc 59028 sc 7325 sc 70655 sc 70654

research category :

Adaptive Immunity, B Cells, Cancer, Cancer Metabolism, Hematopoietic Progenitors, Immunology, Lymphoid, Metabolism, Metabolism Processes, Myeloid, Pathways And Processes, Response To Hypoxia, Stem Cells, Surface Molecules, T Lymphocytic Lineage

synonyms :

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;3.2.2.6;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2.4.99.20;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADPRC 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;T10;CD38;CD38;

gene full name :

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

molecular weight :

34328 MW

protein function :

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

subcellular localization :

Membrane; Single-pass type II membrane protein.

tissue specificity :

Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.

protein name :

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

last modified :

2/6/19 22:57