Anti-Human CD44 Monoclonal Antibody FITC Conjugated, Flow Validated

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Human CD44 Monoclonal Antibody FITC Conjugated, Flow Validated

catalog :

FC00052-FITC

quantity :

100 Tests, 200 Tests

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

Hermes-3

The same clone is also sold as:

Abnova: MAB12311
US Biological: 030854-AP, 030854-APC, 030854, 030854-Biotin

reactivity :

human

application :

flow cytometry

product information

SKU :

FC00052-FITC

Product Name :

Anti-Human CD44 Monoclonal Antibody FITC Conjugated, Flow Validated

Size :

100 Tests, 200 Tests

Clonality :

Monoclonal

Clone Number :

Hermes-3

Host :

Mouse

Conjugate :

FITC

Reactivity :

Human

Application(s) :

Flow Cytometry

Application Details :

Flow Cytometry

Description :

Boster Bio Anti-Human CD44 Monoclonal Antibody FITC Conjugated, Flow Validated catalog # FC00052-FITC. Tested in Flow Cytometry applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CD44

Uniprot ID :

P16070

Immunogen :

CD44 recombinant protein

Form :

Liquid, in PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Contents :

PBS, pH7.2, <0.09% NaN3 and 0.2% (w/v) BSA

Purification :

Affinity column chromatography

Gene Full Name :

CD44 antigen

Synonyms :

CD44 antigen; CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD44; CD44; LHR, MDU2, MDU3, MIC4;

Molecular Weight :

81538 MW

Protein Function :

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).

Subcellular Localization :

Cell membrane ; Single-pass type I membrane protein. Colocalizes with actin in membrane protrusions at wounding edges.

Tissue Specificity :

Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.

Research Category :

Cancer, Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, Mesenchymal Stem Cells, Myeloid, Stem Cells, Surface Molecules, T Lymphocytic Lineage, Tumor Biomarkers, Tumor Immunology