Human BMP-7 ELISA Kit EZ-Set™ (DIY Antibody Pairs) | Boster EZ0884 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human BMP-7 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

catalog :

EZ0884

quantity :

For 5 plates, 96 wells each

product information

SKU :

EZ0884

Product Name :

Human BMP-7 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Size :

For 5 plates, 96 wells each

Description :

Human BMP-7 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human BMP7 in bone tissue, cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10 pg/ml. Product Features: Your ideal low cost ELISA solution. EZ Set™ ELISA kit contains the necessary core reagents develop and run the ELISA, including ELISA-optimized matched antibody pairs, recombinant protein standards, and HRP conjugated Avidin-Biotin-Complex (ABC). One kit is sufficient for developing 5 plates (96 well format). EZ Set™ ELISAs are ideal for experienced ELISA users on a budget and great for exploratory work--a fast and easy way to identify the relevant protein targets of interest/relevance to your studies.

Reactivity :

Human

Application :

ELISA

Gene Name :

BMP7

Uniprot ID :

P18075

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S293-H431

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

bone tissue, cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

bone morphogenetic protein 7

Synonyms :

Bone morphogenetic protein 7; BMP-7; Osteogenic protein 1; OP-1; Eptotermin alfa; BMP7; OP1

Protein Name :

Bone morphogenetic protein 7

Molecular Weight :

49313 MW

Protein Function :

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in the kidney and bladder. Lower levels seen in the brain.

Background :

Bone morphogenetic protein 7 or BMP7 (also known as osteogenic protein-1 or OP-1) is a protein that in humans is encoded by the BMP7 gene.The protein encoded by this gene is a member of the TGF-beta superfamily. Like other members of the bone morphogenetic protein family of proteins, it plays a key role in the transformation of mesenchymal cells into bone and cartilage. It is inhibited by noggin and a similar protein, chordin, which are expressed in the Spemann-Mangold Organizer. BMP7 may be involved in bone homeostasis. It is expressed in the brain, kidneys and bladder.

Research Category :

Extracellular Matrix, Growth Factors/Hormones, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Metabolic Signaling Pathways, Metabolism, Nervous System Development, Organogenesis, Pathways And Processes, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Structures, Tgf Beta