ELISA/assay

Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

EZ0702

For 5 plates, 96 wells each

215 USD

Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

For 5 plates, 96 wells each

215 USD

Human CD40/TNFRSF5 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human CD40 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. Sensitivity: 1 pg/ml. Product Features: Your ideal low cost ELISA solution. EZ Set™ ELISA kit contains the necessary core reagents develop and run the ELISA, including ELISA-optimized matched antibody pairs, recombinant protein standards, and HRP conjugated Avidin-Biotin-Complex (ABC). One kit is sufficient for developing 5 plates (96 well format). EZ Set™ ELISAs are ideal for experienced ELISA users on a budget and great for exploratory work--a fast and easy way to identify the relevant protein targets of interest/relevance to your studies.

Human

ELISA

CD40

P25942

Expression system for standard: NS0; Immunogen sequence: E21-R193

There is no detectable cross-reactivity with other relevant proteins.

15.6 pg/ml - 1,000 pg/ml

<1 pg/ml

cell culture supernatants, serum, plasma (heparin, EDTA), saliva, urine and human milk

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Tumor necrosis factor receptor superfamily member 5

Tumor necrosis factor receptor superfamily member 5;B-cell surface antigen CD40;Bp50;CD40L receptor;CDw40;CD40;CD40;TNFRSF5;

Tumor necrosis factor receptor superfamily member 5

30619 MW

Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Isoform I: Cell membrane; Single-pass type I membrane protein.

B-cells and in primary carcinomas.

Contains 4 TNFR-Cys repeats.

CD40 is a cell surface receptor that is expressed on the surface of all mature B cells, most mature B-cell malignancies, and some early B-cell acute lymphocytic leukemias, but is not expressed on plasma cells. The CD40 gene is localized to the long arm of chromosome 20, bands q12-q13.2. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.

Lymphoid, Myeloid, Stem Cells, Vascular Inflammation