Human IL-4 ELISA Kit EZ-Set™ (DIY Antibody Pairs) | Boster EZ0404 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-4 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

catalog :

EZ0404

quantity :

For 5 plates, 96 wells each, reagents only, plates are not included

price :

220 USD

more info or order :

Boster product webpage

citations: 1

Reference
Sarangi A, Mohapatra P, Dalai R, Sarangi A. Serum IL-4, IL-12 and TNF-alpha in malaria: a comparative study associating cytokine responses with severity of disease from the Coastal Districts of Odisha. J Parasit Dis. 2014;38:143-7 pubmed publisher

image

image 1 :

Human IL-4 EZ Set ELISA Kit standard curve

product information

SKU :

EZ0404

Product Name :

Human IL-4 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Size :

For 5 plates, 96 wells each, reagents only, plates are not included

Price :

220 USD

Description :

Human IL-4 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Human IL4 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1.5 pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL4

Uniprot ID :

D4HNR6

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: H25-S153

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<1.5 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-4

Synonyms :

Interleukin-4 ;IL-4 ;B-cell stimulatory factor 1 ;Lymphocyte stimulatory factor 1 ;IL4 ;hCG_24113 ;

Protein Name :

Interleukin-4

Molecular Weight :

17492 MW

Protein Function :

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.

Subcellular Localization :

Secreted .

Background :

Interleukin-4 (IL-4), also knowns as a B-cell stimulatory factor1 (BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells.The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-directed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis. The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5. The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.

more info or order :

Boster product webpage