Mouse BMP-2 ELISA Kit EZ-Set™ (DIY Antibody Pairs) | Boster EZ0313 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse BMP-2 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

catalog :

EZ0313

quantity :

For 5 plates, 96 wells each, reagents only, plates are not included

product information

SKU :

EZ0313

Product Name :

Mouse BMP-2 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Size :

For 5 plates, 96 wells each, reagents only, plates are not included

Description :

Mouse BMP-2 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2 pg/ml. Product Features: Your ideal low cost ELISA solution. EZ Set™ ELISA kit contains the necessary core reagents develop and run the ELISA, including ELISA-optimized matched antibody pairs, recombinant protein standards, and HRP conjugated Avidin-Biotin-Complex (ABC). One kit is sufficient for developing 5 plates (96 well format). EZ Set™ ELISAs are ideal for experienced ELISA users on a budget and great for exploratory work--a fast and easy way to identify the relevant protein targets of interest/relevance to your studies.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

BMP2

Uniprot ID :

P21274

Immunogen :

Expression system for standard: CHO; Immunogen sequence: Q283-R396

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

bone tissue, cell culture supernatants and serum

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Bone morphogenetic protein 2

Synonyms :

Bone morphogenetic protein 2;BMP-2;Bone morphogenetic protein 2A;BMP-2A;Bmp2;Bmp-2;

Protein Name :

Bone morphogenetic protein 2

Molecular Weight :

44525 MW

Protein Function :

Induces cartilage and bone formation.

Subcellular Localization :

Secreted.

Background :

Bone morphogenetic protein-2 (BMP-2, BMP 2A) belongs to the transforming growth factor beta (TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice. BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis. Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion. The standard product used in this kit is recombinant mouse BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa.

Research Category :

Signal Transduction, Signaling Pathways, Stem Cells, Structures, Tgf Beta