TNF Receptor II Colorimetric Cell-Based ELISA | Boster EKC1688 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

TNF Receptor II Colorimetric Cell-Based ELISA

catalog :

EKC1688

quantity :

1 kit, containing 1 plates and all necessary reagents

product information

SKU :

EKC1688

Product Name :

TNF Receptor II Colorimetric Cell-Based ELISA

Size :

1 kit, containing 1 plates and all necessary reagents

Description :

The TNF Receptor II Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TNF Receptor II protein expression profile in cells. The kit can be used for measuring the relative amounts of TNF Receptor II in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TNF Receptor II.

Reactivity :

Human,Mouse,Rat

Application :

ELISA

Gene Name :

TNFRSF1B

Uniprot ID :

P20333

Assay Range :

> 5000 Cells

Sensitivity :

>5000 cells

Storage :

4°C/6 Months

Gene Full Name :

Tumor necrosis factor receptor superfamily member 1B

Synonyms :

Tumor necrosis factor receptor superfamily member 1B;Tumor necrosis factor receptor 2;TNF-R2;Tumor necrosis factor receptor type II;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b;Etanercept;Tumor necrosis factor receptor superfamily member 1b, membrane form;Tumor necrosis factor-binding protein 2;TBP-2;TBPII;TNFRSF1B;TNFBR, TNFR2;

Molecular Weight :

48291 MW

Protein Function :

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

Subcellular Localization :

Isoform 1: Cell membrane; Single-pass type I membrane protein.