Granzyme B Colorimetric Cell-Based ELISA Kit | Boster EKC1249 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Granzyme B Colorimetric Cell-Based ELISA Kit

catalog :

EKC1249

quantity :

1 kit, containing 1 plates and all necessary reagents

product information

SKU :

EKC1249

Product Name :

Granzyme B Colorimetric Cell-Based ELISA Kit

Size :

1 kit, containing 1 plates and all necessary reagents

Description :

The Granzyme B Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Granzyme B protein expression profile in cells. The kit can be used for measuring the relative amounts of Granzyme B in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Granzyme B.

Reactivity :

Human,Mouse,Rat

Application :

ELISA

Gene Name :

GZMB

Uniprot ID :

P10144

Assay Range :

> 5000 Cells

Sensitivity :

>5000 cells

Storage :

4°C/6 Months

Gene Full Name :

Granzyme B

Synonyms :

Granzyme B;3.4.21.79;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E;GZMB;CGL1, CSPB, CTLA1, GRB;

Molecular Weight :

27716 MW

Protein Function :

This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Subcellular Localization :

Cytoplasmic granule . Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells.