Galectin 3 Colorimetric Cell-Based ELISA Kit | Boster EKC1233 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Galectin 3 Colorimetric Cell-Based ELISA Kit

catalog :

EKC1233

quantity :

1 kit, containing 1 plates and all necessary reagents

product information

SKU :

EKC1233

Product Name :

Galectin 3 Colorimetric Cell-Based ELISA Kit

Size :

1 kit, containing 1 plates and all necessary reagents

Description :

The Galectin 3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Galectin 3 protein expression profile in cells. The kit can be used for measuring the relative amounts of Galectin 3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Galectin 3.

Reactivity :

Human,Mouse,Rat

Application :

ELISA

Gene Name :

LGALS3

Uniprot ID :

P17931

Assay Range :

> 5000 Cells

Sensitivity :

>5000 cells

Storage :

4°C/6 Months

Gene Full Name :

Galectin-3

Synonyms :

Galectin-3;Gal-3;35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Galactose-specific lectin 3;Galactoside-binding protein;GALBP;IgE-binding protein;L-31;Laminin-binding protein;Lectin L-29;Mac-2 antigen;LGALS3;MAC2;

Molecular Weight :

26152 MW

Protein Function :

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Subcellular Localization :

Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.

Tissue Specificity :

A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.