Mouse SPARCL1/SPARC-like protein 1 ELISA Kit PicoKine®

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse SPARCL1/SPARC-like protein 1 ELISA Kit PicoKine®

catalog :

EK2125

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK2125

Product Name :

Mouse SPARCL1/SPARC-like protein 1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse SPARCL1 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse SPARCL1 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 50pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Sparcl1

Uniprot ID :

P70663

Immunogen :

Expression system for standard: NS0; Immunogen sequence: I17-F650

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

a monoclonal antibody from rat, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

SPARC-like 1

Synonyms :

SPARC-like protein 1; Extracellular matrix protein 2; Matrix glycoprotein Sc1; Sparcl1; Ecm2; Sc1

Protein Name :

SPARC-like protein 1

Subcellular Localization :

Extracellular matrix

Tissue Specificity :

Highest expression in brain. Moderate levels in heart, adrenal gland, epididymis and lung. Low levels in kidney, eye, liver, spleen, submandibular gland and testis.

Background :

SPARCL1 (SPARC-Like Protein 1), also known as HEVIN, is a protein that in humans is encoded by the SPARCL1 gene. It is mapped to 5 E5; 5 50.55 cM. The cells in high endothelial venules (HEVs) in lymphoid tissues have a plump, almost cuboidal, appearance and support high levels of lymphocyte extravasation from blood, possibly due to the presence of desmosome-like junctions rather than tight junctions in the HEVs. In chronic inflammation, the activated endothelium of nonlymphoid tissues acquires an HEV-like morphology and function. SPARCL1 is highly expressed in HEV and is thought to contribute to the induction or maintenance of features of the HEV endothelium that facilitate lymphocyte migration.