Human Arylsulfatase A/ARSA ELISA Kit PicoKine® | Boster EK2077 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Arylsulfatase A/ARSA ELISA Kit PicoKine®

catalog :

EK2077

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK2077

Product Name :

Human Arylsulfatase A/ARSA ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human ARSA ELISA Kit PicoKine® (96 Tests). Quantitate Human ARSA in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

ARSA

Uniprot ID :

P15289

Immunogen :

Expression system for standard: NS0; Immunogen sequence: R19-A507

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

arylsulfatase A

Synonyms :

Arylsulfatase A; ASA; Cerebroside-sulfatase; ARSA

Protein Function :

Hydrolyzes cerebroside sulfate.

Subcellular Localization :

Endoplasmic reticulum. Lysosome.

Background :

Arylsulfatase A (or cerebroside-sulfatase) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into cerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. It is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.