Rat SEMA6C ELISA Kit PicoKine® | Boster EK2059 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat SEMA6C ELISA Kit PicoKine®

catalog :

EK2059

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK2059

Product Name :

Rat SEMA6C ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat SEMA6C ELISA Kit PicoKine® (96 Tests). Quantitate Rat Sema6c in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 50pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

Sema6c

Uniprot ID :

Q9WTL3

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A24-P635

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

semaphorin 6C

Synonyms :

Semaphorin-6C; Semaphorin-Y; Sema Y; Sema6c; Semay

Protein Function :

Shows growth cone collapsing activity on dorsal root ganglion (DRG) neurons in vitro. May be a stop signal for the DRG neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections.

Subcellular Localization :

Cell membrane. Single-pass type I membrane protein.

Tissue Specificity :

Expressed in many regions of the developing nervous system, probably in neurons and their precursors, but also in nonneural tissue such as immature muscle and dermis. In adult, strong expression in the skeletal muscle and moderate expression in the brain, where cerebellum shows the highest expression. Also expressed in almost all areas of the CNS.

Background :

Semaphorin-6C is a protein that in humans is encoded by the SEMA6C gene. This gene is mapped to 2q34. This gene product is a member of the semaphoring family of proteins. Semaphorins represent important molecular signals controlling multiple aspects of the cellular response that follows CNS injury, and thus may play an important role in neural regeneration.