Human ANGPTL2 ELISA Kit PicoKine® | Boster EK2039 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human ANGPTL2 ELISA Kit PicoKine®

catalog :

EK2039

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK2039

Product Name :

Human ANGPTL2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human ANGPTL2 ELISA Kit PicoKine® (96 Tests). Quantitate Human ANGPTL2 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50 pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

ANGPTL2

Uniprot ID :

Q9UKU9

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q23-H493

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

angiopoietin like 2

Synonyms :

Angiopoietin-related protein 2; Angiopoietin-like protein 2

Protein Name :

Angiopoietin-related protein 2

Protein Function :

Induces sprouting in endothelial cells through an autocrine and paracrine action.

Subcellular Localization :

Secreted.

Tissue Specificity :

Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.

Background :

Angiopoietin-related protein 2 also known as angiopoietin-like protein 2 is a protein that in humans is encoded by the ANGPTL2 gene. This gene is mapped to 9q33.3. Angiopoietin-like protein 2 maintains tissue homeostasis by promoting adaptive inflammation and subsequent tissue reconstruction, whereas an excess of ANGPTL2 activation induced by prolonged stress promotes the breakdown of tissue homeostasis due to chronic inflammation, promoting the development of metabolic diseases. ANGPTL2 has a role also in angiogenesis, in tissue repair, in obesity, in atherosclerotic diseases and finally in carcinogenesis. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.

Research Category :

Angiogenesis, Cardiovascular, Growth Factors, Hematopoietic Progenitors, Stem Cells