Human TCN2/Transcobalamin-2 ELISA Kit PicoKine® | Boster EK2038 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TCN2/Transcobalamin-2 ELISA Kit PicoKine®

catalog :

EK2038

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK2038

Product Name :

Human TCN2/Transcobalamin-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human TCN2 ELISA Kit PicoKine® (96 Tests). Quantitate Human TCN2 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

TCN2

Uniprot ID :

P20062

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E19-W427

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

transcobalamin 2

Synonyms :

Transcobalamin-2; TC-2; Transcobalamin II; TC II; TCII; TCN2; TC2

Protein Name :

Transcobalamin-2

Protein Function :

Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.

Subcellular Localization :

Secreted.

Background :

TCN2 (Transcobalamin II; also TC-2 or TC) is a 42-44 kDa, monomeric, secreted member of the eukaryotic cobalamin transport family of molecules. This gene is mapped to 22q12.2. This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.

Research Category :

Cardiovascular, Cofactors, Vitamins / Minerals, Metabolism, Pathways And Processes, Serum Proteins, Signal Transduction, Vitamins / Minerals