Human LTBR ELISA Kit PicoKine® | Boster EK2002 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human LTBR ELISA Kit PicoKine®

catalog :

EK2002

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK2002

Product Name :

Human LTBR ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human LTBR ELISA Kit PicoKine® (96 Tests). Quantitate Human LTBR in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

LTBR

Uniprot ID :

P36941

Immunogen :

Expression system for standard: CHO; Immunogen sequence: Q31-M227

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

lymphotoxin beta receptor

Synonyms :

Tumor necrosis factor receptor superfamily member 3; Lymphotoxin-beta receptor; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor type III; TNF-RIII; TNFR-III; LTBR; D12S370; TNFCR; TNFR3; TNFRSF3

Protein Name :

Tumor necrosis factor receptor superfamily member 3

Protein Function :

Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

Subcellular Localization :

Membrane. Single-pass type I membrane protein.

Background :

Lymphotoxin beta receptor (LTBR), also known as tumor necrosis factor receptor superfamily member 3 (TNFRSF3), is a cell surface receptor for lymphotoxin involved in apoptosis and cytokine release. This gene is mapped to 12p13.31. This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

Research Category :

Apoptosis, Associated Proteins, Cell Biology, Epigenetics and Nuclear Signaling, Growth Factors/Hormones, Intracellular, Nfkb Pathway, Nuclear Signaling Pathways, Signal Transduction