Human FUT8 ELISA Kit PicoKine® | Boster EK1990 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human FUT8 ELISA Kit PicoKine®

catalog :

EK1990

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1990

Product Name :

Human FUT8 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human FUT8 ELISA Kit PicoKine® (96 Tests). Quantitate Human FUT8 in cell culture supernatants, serum and plasma (heparin or EDTA) . Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

FUT8

Uniprot ID :

Q9BYC5

Immunogen :

Expression system for standard: NS0; Immunogen sequence: R31-K575

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin or EDTA)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

fucosyltransferase 8

Synonyms :

Alpha- (1,6)-fucosyltransferase; Alpha1-6FucT; Fucosyltransferase 8; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; FUT8

Protein Function :

Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.

Subcellular Localization :

Golgi stack membrane. Single-pass type II membrane protein.

Background :

Alpha- (1,6)-fucosyltransferase is an enzyme that in humans is encoded by the FUT8 gene. It is mapped to 14q23.3. This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.

Research Category :

Amino Acid Metabolism, Amino Acids, Cancer, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Signal Transduction, Tumor Biomarkers