Human TREML2 ELISA Kit PicoKine® | Boster EK1985 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TREML2 ELISA Kit PicoKine®

catalog :

EK1985

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1985

Product Name :

Human TREML2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human TREML2 ELISA Kit PicoKine® (96 Tests). Quantitate Human TREML2 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

TREML2

Uniprot ID :

Q5T2D2

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: G19-S268

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

triggering receptor expressed on myeloid cells like 2

Synonyms :

Trem-like transcript 2 protein; TLT-2; Triggering receptor expressed on myeloid cells-like protein 2; TREML2; C6orf76, TLT2; UNQ6268/PRO20473

Protein Function :

Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.

Subcellular Localization :

Cell membrane. Single-pass type I membrane protein.

Tissue Specificity :

Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation.

Background :

TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. This gene is mapped to 6p21.1.

Research Category :

Adaptive Immunity, B Cells, Immunology, Innate Immunity, Macrophage / Inflamm., Non-Cd, T Cells