Human CD300F ELISA Kit PicoKine® | Boster EK1982 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CD300F ELISA Kit PicoKine®

catalog :

EK1982

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1982

Product Name :

Human CD300F ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human CD300F ELISA Kit PicoKine® (96 Tests). Quantitate Human CD300LF in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CD300LF

Uniprot ID :

Q8TDQ1

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: T20-S156

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

CD300 molecule like family member f

Synonyms :

CMRF35-like molecule 1; CLM-1; CD300 antigen-like family member F; Immune receptor expressed on myeloid cells 1; IREM-1; Immunoglobulin superfamily member 13; IgSF13; NK inhibitory receptor; CD300f; CD300LF; CD300F; CLM1; IGSF13; IREM1; NKIR; UNQ3105/PRO1

Protein Function :

Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apo

Subcellular Localization :

Cell membrane. Single-pass type I membrane protein.

Tissue Specificity :

Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocy

Background :

CMRF35-like molecule 1 is a protein that in humans is encoded by the CD300LF gene. It is mapped to 17q25.1. This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants.

Research Category :

Immunoglobulins, Immunology, Receptors