Rat FLRT2 ELISA Kit PicoKine® | Boster EK1973 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat FLRT2 ELISA Kit PicoKine®

catalog :

EK1973

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1973

Product Name :

Rat FLRT2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat FLRT2 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Flrt2 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

Flrt2

Uniprot ID :

D3ZTV3

Immunogen :

Expression system for standard: NS0; Immunogen sequence: C36-T660

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

fibronectin leucine rich transmembrane protein 2

Synonyms :

Leucine-rich repeat transmembrane protein FLRT2; Fibronectin-like domain-containing leucine-rich transmembrane protein 2; Flrt2

Protein Function :

Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of c

Subcellular Localization :

Extracellular matrix. Secreted. Endoplasmic reticulum membrane. Microsome membrane. Cell membrane. Single-pass membrane protein. Focal adhesion. Synaptosome.

Tissue Specificity :

Detected in brain.

Background :

Fibronectin leucine-rich repeat transmembrane protein FLRT2 is a protein that in humans is encoded by the FLRT2 gene. It is mapped to 6q31. This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants.

Research Category :

Growth Factors/Hormones, Mesenchymal Stem Cells, Signal Transduction, Stem Cells