Human JAM-B/JAM2 ELISA Kit PicoKine® | Boster EK1842 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human JAM-B/JAM2 ELISA Kit PicoKine®

catalog :

EK1842

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1842

Product Name :

Human JAM-B/JAM2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human JAM-B/JAM2 ELISA Kit PicoKine® (96 Tests). Quantitate Human JAM2 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

JAM2

Uniprot ID :

P57087

Immunogen :

Expression system for standard: NS0; Immunogen sequence: F29-S238

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

junctional adhesion molecule 2

Synonyms :

Junctional adhesion molecule B; JAM-B; Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAM; CD322; JAM2; C21orf43; VEJAM; UNQ219/PRO245

Protein Function :

May play a role in the processes of lymphocyte homing to secondary lymphoid organs.

Subcellular Localization :

Cell membrane, Single-pass type I membrane protein, Tight junction

Tissue Specificity :

Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.

Background :

Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene. It is mapped to 21q21.3. This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.

Research Category :

Cardiovascular, Cell Adhesion, Cell Adhesion Molecules, Cytoskeleton / Ecm, Signal Transduction, Tight Junctions, Vasculature