Human REG1A ELISA Kit PicoKine® | Boster EK1812 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human REG1A ELISA Kit PicoKine®

catalog :

EK1812

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1812

Product Name :

Human REG1A ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human REG1A ELISA Kit PicoKine® (96 Tests). Quantitate Human REG1A in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

REG1A

Uniprot ID :

P05451

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q23-N166

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

regenerating family member 1 alpha

Synonyms :

Lithostathine-1-alpha; Islet cells regeneration factor; ICRF; Islet of Langerhans regenerating protein; REG; Pancreatic stone protein; PSP; Pancreatic thread protein; PTP; Regenerating islet-derived protein 1-alpha; REG-1-alpha; Regenerating protein I alpha; REG1A; PSPS1

Protein Function :

Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

Subcellular Localization :

Secreted

Tissue Specificity :

In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients.

Background :

This gene is a type I subclass member of the Reg gene family. It is mapped to 2p12. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

Research Category :

Cancer, Cell Biology, Tumor Biomarkers