Human EphA1 ELISA Kit PicoKine® | Boster EK1796 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human EphA1 ELISA Kit PicoKine®

catalog :

EK1796

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1796

Product Name :

Human EphA1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human EphA1 ELISA Kit PicoKine® (96 Tests). Quantitate Human EPHA1 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate ). Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

EPHA1

Uniprot ID :

P21709

Immunogen :

Expression system for standard: NS0; Immunogen sequence: K26-E547

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

EPH receptor A1

Protein Function :

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred

Tissue Specificity :

Overexpressed in several carcinomas.

Background :

EPHA1, EPH receptor A1, is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The EPHA1 gene is mapped to 7q34-q35. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.

Research Category :

Neuroscience, Neurotransmission, Protein Phosphorylation, Receptor Tyrosine Kinases, Receptors / Channels, Signal Transduction, Tyrosine Kinases