Human PROS1 / Protein S ELISA Kit PicoKine® | Boster EK1739 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human PROS1 / Protein S ELISA Kit PicoKine®

catalog :

EK1739

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1739

Product Name :

Human PROS1 / Protein S ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human PROS1 / Protein S ELISA Kit PicoKine® (96 Tests). Quantitate Human PROS1 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate ). Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

PROS1

Uniprot ID :

P07225

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A42-S676

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

A monoclonal antibody from mouse, a biotinylated detection polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

protein S

Synonyms :

Vitamin K-dependent protein S; PROS1; PROS

Protein Function :

Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.

Subcellular Localization :

Secreted

Tissue Specificity :

Plasma

Background :

This PROS1 gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. This gene is mapped to 3q11.1. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4bbinding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Research Category :

Cardiovascular, Serum Proteins