Human Serpin G1 ELISA Kit PicoKine® | Boster EK1667 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Serpin G1 ELISA Kit PicoKine®

catalog :

EK1667

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1667

Product Name :

Human Serpin G1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Serpin G1 ELISA Kit PicoKine® (96 Tests). Quantitate Human SERPING1 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

SERPING1

Uniprot ID :

P05155

Immunogen :

Expression system for standard: NS0; Immunogen sequence: N23-A500

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

serpin family G member 1

Synonyms :

Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; Serpin G1; SERPING1; C1IN; C1NH

Protein Function :

Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein.

Subcellular Localization :

Secreted.

Background :

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Research Category :

Cardiovascular, Complement, Immunology, Innate Immunity