Human IL-38/IL1F10 ELISA Kit PicoKine® | Boster EK1662 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-38/IL1F10 ELISA Kit PicoKine®

catalog :

EK1662

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1662

Product Name :

Human IL-38/IL1F10 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human IL-38/IL1F10 ELISA Kit PicoKine® (96 Tests). Quantitate Human IL1F10 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL1F10

Uniprot ID :

Q8WWZ1

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: M1-W152

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

interleukin 1 family member 10

Synonyms :

Interleukin-1 family member 10; IL-1F10; Family of interleukin 1-theta; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; Interleukin-38; IL-38; IL1F10; FIL1T; IL1HY2; IL38; FKSG75; UNQ6119/PRO20041

Protein Function :

Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.

Background :

Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene. The protein encoded by thi s gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses.

Research Category :

Cytokines, Immunology, Innate Immunity, Interleukins