Human IL-19/Interleukin-19 ELISA Kit PicoKine® | Boster EK1638 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-19/Interleukin-19 ELISA Kit PicoKine®

catalog :

EK1638

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1638

Product Name :

Human IL-19/Interleukin-19 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human IL-19 ELISA Kit PicoKine® (96 Tests). Quantitate Human IL19 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

IL19

Uniprot ID :

Q9UHD0

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: L25-A177

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

interleukin 19

Synonyms :

Interleukin-19; IL-19; Melanoma differentiation-associated protein-like protein; NG.1; IL19; ZMDA1

Protein Function :

May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis (By similarity).

Subcellular Localization :

Secreted.

Background :

Interleukin 19 (IL19) is a protein that in humans is encoded by the IL19 gene. The protein encoded by this gene is a cytokine that belongs to the IL-10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the interleukin-20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.

Research Category :

Cytokines, Immunology, Innate Immunity, Interleukins