Human PLA2G7/Lp-PLA2 ELISA Kit PicoKine® | Boster EK1637 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human PLA2G7/Lp-PLA2 ELISA Kit PicoKine®

catalog :

EK1637

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1637

Product Name :

Human PLA2G7/Lp-PLA2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human PLA2G7/Lp-PLA2 ELISA Kit PicoKine® (96 Tests). Quantitate Human PLA2G7 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

PLA2G7

Uniprot ID :

Q13093

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: F22-N441

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

0.78 ng/ml - 50 ng/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

phospholipase A2 group VII

Synonyms :

Platelet-activating factor acetylhydrolase; PAF acetylhydrolase; 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; Group-VIIA phospholipase A2; gVIIA-PLA2; LDL-associated phospholipase A2; LDL-PLA (2); PAF 2-acylhydrolase; PLA2G7; PAFAH

Protein Name :

Platelet-activating factor acetylhydrolase

Protein Function :

Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids.

Subcellular Localization :

Secreted, extracellular space.

Tissue Specificity :

Plasma

Background :

Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45-kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.

Research Category :

Cardiovascular, Immunology, Innate Immunity, Macrophage / Inflamm., Platelets, Secreted Molecules