Human Bikunin / alpha 1 Microglobulin ELISA Kit PicoKine®

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Bikunin / alpha 1 Microglobulin ELISA Kit PicoKine®

catalog :

EK1598

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1598

Product Name :

Human Bikunin / alpha 1 Microglobulin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Bikunin / alpha 1 Microglobulin ELISA Kit PicoKine® (96 Tests). Quantitate Human AMBP in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

AMBP

Uniprot ID :

P02760

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A206-N352

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

15.6 pg/ml - 1,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

alpha-1-microglobulin/bikunin precursor

Synonyms :

Protein AMBP; Alpha-1-microglobulin; Protein HC; Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge; Inter-alpha-trypsin inhibitor light chain; ITI-LC; Bikunin; EDC1; HI-30; Uronic-acid-rich protein; Trypstatin; AMBP; HCP; ITIL

Protein Function :

Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha- trypsin inhibitor is present in plasma and urine.

Background :

Protein AMBP is a protein that in humans is encoded by the AMBP gene. This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes.

Research Category :

Cancer, Cardiovascular, Cell Biology, Protease Inhibitors, Proteolysis / Ubiquitin, Serum Proteins, Tumor Biomarkers