Human SAP/PTX2/APCS ELISA Kit PicoKine® | Boster EK1557 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human SAP/PTX2/APCS ELISA Kit PicoKine®

catalog :

EK1557

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1557

Product Name :

Human SAP/PTX2/APCS ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human SAP/PTX2 ELISA Kit PicoKine® (96 Tests). Quantitate Human APCS in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

APCS

Uniprot ID :

P02743

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: H20-V223

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

1.56 ng/ml - 100 ng/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Serum amyloid P-component

Synonyms :

Serum amyloid P-component;SAP;9.5S alpha-1-glycoprotein;Serum amyloid P-component (1-203);APCS;PTX2;

Protein Name :

Serum amyloid P-component

Molecular Weight :

25387 MW

Protein Function :

Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

Subcellular Localization :

Secreted.

Tissue Specificity :

Found in serum and urine.

Background :

Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.