Human Syndecan-3/SDC3 ELISA Kit PicoKine® | Boster EK1555 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Syndecan-3/SDC3 ELISA Kit PicoKine®

catalog :

EK1555

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1555

Product Name :

Human Syndecan-3/SDC3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Syndecan-3/SDC3 ELISA Kit PicoKine® (96 Tests). Quantitate Human SDC3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

SDC3

Uniprot ID :

O75056

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A41-V387

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

a monoclonal antibody from mouse, a biotinylated polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Syndecan-3

Synonyms :

Syndecan-3;SYND3;SDC3;KIAA0468;

Protein Name :

Syndecan-3

Molecular Weight :

45497 MW

Protein Function :

Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Expressed in the nervous system, the adrenal gland, and the spleen.

Background :

Syndecan-3 is a protein that in humans is encoded by the SDC3 gene. The protein encoded by this gene belongs to the syndecan proteoglycan family, which was assigned to human chromosome 1p35.2, and it showed that in the mouse the Synd3 gene maps to chromosome 4 near the Lmyc gene. The transfection of SDC3 resulted in the formation of long filopodia-like structures, microspikes, and varicosities in several cell lines. Besides, the gene plays a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity.

Research Category :

Cytoskeleton / Ecm, Signal Transduction