Rabbit GREM2 ELISA Kit PicoKine® | Boster EK1533-RB product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rabbit GREM2 ELISA Kit PicoKine®

catalog :

EK1533-RB

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1533-RB

Product Name :

Rabbit GREM2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rabbit GREM2 ELISA Kit PicoKine® (96 Tests). Quantitate Rabbit GREM2 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 12pg/ml.

Reactivity :

Rabbit

Application :

ELISA

Gene Name :

GREM2

Uniprot ID :

Q9H772

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: R22-Q168

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<12 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Gremlin-2

Synonyms :

Gremlin-2;Cysteine knot superfamily 1, BMP antagonist 2;DAN domain family member 3;Protein related to DAN and cerberus;GREM2;CKTSF1B2, DAND3, PRDC;

Protein Name :

Gremlin-2

Molecular Weight :

19320 MW

Protein Function :

Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity).

Subcellular Localization :

Secreted .

Background :

GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.

Research Category :

Cytokines, Cytoskeleton / Ecm, Embryonic Stem Cells, Extracellular Matrix, Signal Transduction, Stem Cells, Structures