Human PRDX2/Peroxiredoxin-2 ELISA Kit PicoKine® | Boster EK1528 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human PRDX2/Peroxiredoxin-2 ELISA Kit PicoKine®

catalog :

EK1528

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1528

Product Name :

Human PRDX2/Peroxiredoxin-2 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Peroxiredoxin 2 ELISA Kit PicoKine® (96 Tests). Quantitate Human PRDX2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

PRDX2

Uniprot ID :

P32119

Immunogen :

Expression system for standard: NS0; Immunogen sequence: A2-N198

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Peroxiredoxin-2

Synonyms :

Peroxiredoxin-2;1.11.1.15;Natural killer cell-enhancing factor B;NKEF-B;PRP;Thiol-specific antioxidant protein;TSA;Thioredoxin peroxidase 1;Thioredoxin-dependent peroxide reductase 1;PRDX2;NKEFB, TDPX1;

Protein Name :

Peroxiredoxin-2

Molecular Weight :

21892 MW

Protein Function :

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H (2)O (2).

Subcellular Localization :

Cytoplasm

Background :

Peroxiredoxin-2 is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8 (+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. It may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Research Category :

Alzheimer'S Disease, Cancer, Cancer Metabolism, Cell Biology, Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Oxidative Stress, Pathways And Processes, Redox Metabolism