Human BCHE/Butyrylcholinesterase ELISA Kit PicoKine® | Boster EK1507 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human BCHE/Butyrylcholinesterase ELISA Kit PicoKine®

catalog :

EK1507

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1507

Product Name :

Human BCHE/Butyrylcholinesterase ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human BCHE/Butyrylcholinesterase ELISA Kit PicoKine® (96 Tests). Quantitate Human BCHE in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva, urine and human milk. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

BCHE

Uniprot ID :

P06276

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E29-L602

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

625 pg/ml - 40,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA), saliva, urine and human milk

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Cholinesterase

Synonyms :

Cholinesterase;3.1.1.8;Acylcholine acylhydrolase;Butyrylcholine esterase;Choline esterase II;Pseudocholinesterase;BCHE;CHE1;

Protein Name :

Cholinesterase

Molecular Weight :

68418 MW

Protein Function :

Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.

Subcellular Localization :

Secreted .

Tissue Specificity :

Detected in blood plasma (at protein level). Present in most cells except erythrocytes.

Background :

Butyrylcholinesterase is a nonspecific cholinesterase enzyme that in humans is encoded by the BCHE gene. This gene is mapped to 3q26. It is a member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.

Research Category :

Alzheimer'S Disease, Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Neurotransmitter, Pathways And Processes, Signal Transduction