Human Hemopexin ELISA Kit PicoKine® | Boster EK1466 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Hemopexin ELISA Kit PicoKine®

catalog :

EK1466

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1466

Product Name :

Human Hemopexin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Hemopexin ELISA Kit PicoKine® (96 Tests). Quantitate Human HPX in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

HPX

Uniprot ID :

P02790

Immunogen :

Expression system for standard: NS0; Immunogen sequence: T24-H462

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

3.12 ng/ml - 200 ng/ml

Sensitivity :

<50 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Hemopexin

Synonyms :

Hemopexin;Beta-1B-glycoprotein;HPX;

Protein Name :

Hemopexin

Molecular Weight :

51676 MW

Protein Function :

Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed by the liver and secreted in plasma.

Background :

Hemopexin (or haemopexin; HPX), also known as beta-1B-glycoprotein, is a protein that in humans is encoded by the HPX gene and belongs to hemopexin family of proteins. Hemopexin binds heme with the highest affinity of any known protein. Its function is scavenging the heme released or lost by the turnover of heme proteins such as hemoglobin and thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound ligand for internalisation upon interacting with a specific receptor situated on the surface of liver cells. This function of hemopexin is to preserve the body's iron.

Research Category :

Cardiovascular, Cofactors, Vitamins / Minerals, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Metabolism, Pathways And Processes, Signal Transduction, Vitamins / Minerals