Rat MMP-9 ELISA Kit PicoKine® | Boster EK1463 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat MMP-9 ELISA Kit PicoKine®

catalog :

EK1463

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1463

Product Name :

Rat MMP-9 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Rat MMP-9 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Mmp9 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 15pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

Mmp9

Uniprot ID :

P50282

Immunogen :

Expression system for standard: NS0; Immunogen sequence: L35-P708

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<15 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Matrix metalloproteinase-9

Synonyms :

Matrix metalloproteinase-9;MMP-9;3.4.24.35;92 kDa gelatinase;92 kDa type IV collagenase;Gelatinase B;GELB;Mmp9;

Protein Name :

Matrix metalloproteinase-9

Molecular Weight :

78611 MW

Protein Function :

Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).

Subcellular Localization :

Secreted, extracellular space, extracellular matrix .

Background :

Matrix metallopeptidase 9 (MMP-9) is also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB). The 72- and 92-kDa type IV collagenases are members of a group of secreted zinc metalloproteases. The matrix metalloproteinases (MMPs) are able to degrade the extracellular matrix and allow angiogenesis and tumor invasion. MMP-9 is predominantly expressed in neutrophils, macrophages, and mast cells, rather than in oncogene-positive neoplastic cells. The polymorphism of MMP-9 acts as a genetic factor for the development of smoking-induced pulmonary emphysema.

Research Category :

Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis / Ubiquitin, Proteolytic Enzymes, Signal Transduction, Tumor Biomarkers