Human FABP4/A Fabp ELISA Kit PicoKine® | Boster EK1459 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human FABP4/A Fabp ELISA Kit PicoKine®

catalog :

EK1459

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1459

Product Name :

Human FABP4/A Fabp ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human FABP4/A Fabp ELISA Kit PicoKine® (96 Tests). Quantitate Human FABP4 in cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysates. Sensitivity: 15pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

FABP4

Uniprot ID :

P15090

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: M1-A132

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<15 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and cell lysate

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Fatty acid-binding protein, adipocyte

Synonyms :

Fatty acid-binding protein, adipocyte;Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4;FABP4;

Protein Name :

Fatty acid-binding protein, adipocyte

Molecular Weight :

14719 MW

Protein Function :

Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).

Subcellular Localization :

Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export (By similarity).

Background :

FABP4, also known as aP2 (adipocyte Protein 2), encodes the fatty acid binding protein found in adipocytes. The FABP4 gene is mapped to 8q21. FABP4 functions as a cytosolic lipid chaperone in macrophages and is involved in regulating macrophage endoplasmic reticulum (ER) stress. Aditionally, FABP4 protein is expressed in HBEs and is strongly upregulated by both IL4 and IL13 and downregulated by IFN-gamma, suggesting a role in allergic airway inflammation.

Research Category :

Cancer, Cancer Metabolism, Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lipids / Lipoproteins, Mesenchymal Stem Cells, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Lipids And Lipoproteins, Pathways And Processes, Redox Metabolism, Signal Transduction, Stem Cells