Mouse CFD/Adipsin/Complement Factor D ELISA Kit PicoKine®

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CFD/Adipsin/Complement Factor D ELISA Kit PicoKine®

catalog :

EK1420

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1420

Product Name :

Mouse CFD/Adipsin/Complement Factor D ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse Adipsin / CFD / Factor D ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Cfd in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Cfd

Uniprot ID :

P03953

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: I26-S259

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

0.78 ng/ml - 50 ng/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, biotinylated monoclonal antibody from rat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

complement factor D (adipsin)

Synonyms :

Complement factor D; 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Properdin factor D; Cfd; And; Df

Protein Function :

Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.

Subcellular Localization :

Secreted.

Background :

Complement factor D (CFD), also called ADIPSIN or FACTOR D, is a protein which in humans is encoded by the CFD gene. The protein encoded by this gene belongs to the trypsin family of peptidases. It is mapped to 19p13.3. The encoded protein is a component of the alternative complement pathway which is best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. What’s more, Factor D is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis.

Research Category :

Mesenchymal Stem Cells, Stem Cells