Human ANGPTL3 ELISA Kit PicoKine® | Boster EK1374 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human ANGPTL3 ELISA Kit PicoKine®

catalog :

EK1374

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 2

Reference
Mehta N, Qamar A, Qu L, Qasim A, Mehta N, Reilly M, et al. Differential association of plasma angiopoietin-like proteins 3 and 4 with lipid and metabolic traits. Arterioscler Thromb Vasc Biol. 2014;34:1057-63 pubmed publisher
Shoji T, Hatsuda S, Tsuchikura S, Kimoto E, Kakiya R, Tahara H, et al. Plasma angiopoietin-like protein 3 (ANGPTL3) concentration is associated with uremic dyslipidemia. Atherosclerosis. 2009;207:579-84 pubmed publisher

image

image 1 :

Human ANGPTL3 PicoKine ELISA Kit standard curve

product information

SKU :

EK1374

Product Name :

Human ANGPTL3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human ANGPTL3 ELISA Kit PicoKine® (96 Tests). Quantitate Human ANGPTL3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

ANGPTL3

Uniprot ID :

Q9Y5C1

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S17-E460

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Angiopoietin-related protein 3

Synonyms :

Angiopoietin-related protein 3;Angiopoietin-5;ANG-5;Angiopoietin-like protein 3;ANGPTL3;ANGPT5;UNQ153/PRO179;

Protein Name :

Angiopoietin-related protein 3

Molecular Weight :

53637 MW

Subcellular Localization :

Secreted .

Tissue Specificity :

Expressed principally in liver. Weakly expressed in kidney.

Sequence Similarities :

Contains 1 fibrinogen C-terminal domain.

Background :

ANGPTL3, also known as Angiopoietin-like 3 or HYPLl, is a protein that in humans is encoded by the ANGPTL3 gene. It is mapped to 1p31.3. The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. ANGPTL3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. It can inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels.

Research Category :

Angiogenesis, Cancer, Cardiovascular, Energy Metabolism, Energy Transfer Pathways, Growth Factors, Lipid Metabolism, Metabolic Signaling Pathways, Metabolism, Obesity, Pathways And Processes, Signal Transduction

more info or order :

Boster product webpage