Human Biglycan ELISA Kit PicoKine® | Boster EK1357 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Biglycan ELISA Kit PicoKine®

catalog :

EK1357

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Kocbek V, Hevir Kene N, Bersinger N, Mueller M, Rizner T. Increased levels of biglycan in endometriomas and peritoneal fluid samples from ovarian endometriosis patients. Gynecol Endocrinol. 2014;30:520-4 pubmed publisher

image

image 1 :

Human Biglycan PicoKine ELISA Kit standard curve

product information

SKU :

EK1357

Product Name :

Human Biglycan ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human Biglycan ELISA Kit PicoKine® (96 Tests). Quantitate Human BGN in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

BGN

Uniprot ID :

P21810

Immunogen :

Expression system for standard: NS0; Immunogen sequence: D38-K368

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Biglycan

Synonyms :

Biglycan;Bone/cartilage proteoglycan I;PG-S1;BGN;SLRR1A;

Protein Name :

Biglycan

Molecular Weight :

41654 MW

Protein Function :

May be involved in collagen fiber assembly.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix .

Tissue Specificity :

Found in several connective tissues, especially in articular cartilages.

Sequence Similarities :

Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.

Background :

Biglycan (BGN) is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. It is an important structural component of articular cartilage and participates in the assembly of the chondrocyte extracellular matrix through formation of protein interactions with type VI collagen and large proteoglycan aggregates. In humans, Biglycan is encoded by the BGN gene. It is mapped to Xq28. Biglycan is believed to play a role in the mineralisation of bone, and its core protein binds to the growth factors BMP-4 and influences its bioactivity. It has been reported that the presence of biglycan is necessary for BMP-4 to exert its effects on osteoblasts. There is also evidence that biglycan can bind to TGF-beta 1. In addition, Biglycan plays an important role in cell signaling.

Research Category :

Adaptive Immunity, Cardiovascular, Immunology, Innate Immunity, Macrophage / Inflamm., Organelles, Subcellular Markers, T Cells, Tags & Cell Markers

more info or order :

Boster product webpage