Mouse TFPI ELISA Kit PicoKine® | Boster EK1355 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse TFPI ELISA Kit PicoKine®

catalog :

EK1355

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Maroney S, Ferrel J, Pan S, White T, Simari R, McVey J, et al. Temporal expression of alternatively spliced forms of tissue factor pathway inhibitor in mice. J Thromb Haemost. 2009;7:1106-13 pubmed publisher

image

image 1 :

Mouse TFPI PicoKine ELISA Kit standard curve

product information

SKU :

EK1355

Product Name :

Mouse TFPI ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Mouse TFPI ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tfpi in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

TFPI

Uniprot ID :

O54819

Immunogen :

Expression system for standard: NS0; Immunogen sequence: L29-N306

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Tissue factor pathway inhibitor

Synonyms :

Tissue factor pathway inhibitor;TFPI;Extrinsic pathway inhibitor;EPI;Lipoprotein-associated coagulation inhibitor;LACI;Tfpi;

Protein Name :

Tissue factor pathway inhibitor

Molecular Weight :

34987 MW

Protein Function :

Inhibits factor X (X (a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma (By similarity).

Subcellular Localization :

Secreted.

Tissue Specificity :

Isoform alpha is expressed in heart and spleen; isoform beta in heart and lung.

Background :

TFPI (Tissue factor pathway inhibitor),also known as EPI, LACI or TFPI1, is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. TFPI consists of a highly negatively-charged amino-terminus, three tandemly-linked Kunitz domains, and a highly positively-charged carboxy-terminus. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.

Research Category :

Cardiovascular, Platelets

more info or order :

Boster product webpage