Mouse ANGPTL3 ELISA Kit PicoKine® | Boster EK1352 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse ANGPTL3 ELISA Kit PicoKine®

catalog :

EK1352

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1352

Product Name :

Mouse ANGPTL3 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse ANGPTL3 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Angptl3 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

ANGPTL3

Uniprot ID :

Q9R182

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S17-T455

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Angiopoietin-related protein 3

Synonyms :

Angiopoietin-related protein 3;Angiopoietin-like protein 3;Angptl3;

Protein Name :

Angiopoietin-related protein 3

Molecular Weight :

52543 MW

Subcellular Localization :

Secreted .

Background :

ANGPTL3, also known as Angiopoietin-like 3 or HYPLl, is a protein that in humans is encoded by the ANGPTL3 gene. It is mapped to 1p31.3. The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. ANGPTL3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. It can inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels.

Research Category :

Angiogenesis, Cancer, Cardiovascular, Energy Metabolism, Energy Transfer Pathways, Growth Factors, Lipid Metabolism, Metabolic Signaling Pathways, Metabolism, Obesity, Pathways And Processes, Signal Transduction