Mouse IL-20/Interleukin-20 ELISA Kit PicoKine® | Boster EK1350 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse IL-20/Interleukin-20 ELISA Kit PicoKine®

catalog :

EK1350

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1350

Product Name :

Mouse IL-20/Interleukin-20 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse IL-20 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Il20 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

IL20

Uniprot ID :

Q9JKV9

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: L25-E176

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-20

Synonyms :

Interleukin-20;IL-20;Cytokine Zcyto10;Il20;Zcyto10;

Protein Name :

Interleukin-20

Molecular Weight :

20098 MW

Protein Function :

Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

Subcellular Localization :

Secreted.

Background :

IL-20, also known as Interleukin 20 or Zcyto10, is a protein that in humans is encoded by the IL20 gene. This gene is mapped to 1q32.1. IL-20 is a protein belonging to the IL-10 family of cytokines. This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells.

Research Category :

Cell Type Markers, Cytokines, Immunology, Innate Immunity, Interleukins