Human Mesothelin ELISA Kit PicoKine® | Boster EK1338 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Mesothelin ELISA Kit PicoKine®

catalog :

EK1338

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
BostancÄ± O, Kemik O, Kemik A, Battal M, Demir U, Purisa S, et al. Preoperative serum levels of mesothelin in patients with colon cancer. Dis Markers. 2014;2014:161954 pubmed publisher

image

image 1 :

Human Mesothelin PicoKine ELISA Kit standard curve

product information

SKU :

EK1338

Product Name :

Human Mesothelin ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human Mesothelin ELISA Kit PicoKine® (96 Tests). Quantitate Human MSLN in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva and urine. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

MSLN

Uniprot ID :

Q13421

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E296-G580

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA), saliva and urine

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Mesothelin

Synonyms :

Mesothelin;CAK1 antigen;Pre-pro-megakaryocyte-potentiating factor;Megakaryocyte-potentiating factor;MPF;Mesothelin, cleaved form;MSLN;MPF;

Protein Name :

Mesothelin

Molecular Weight :

68986 MW

Protein Function :

Membrane-anchored forms may play a role in cellular adhesion.

Subcellular Localization :

Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus.

Tissue Specificity :

Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).

Background :

Mesothelin, also known as MSLN or MPF is a protein that in humans is encoded by the MSLN gene. This gene is mapped to 16p13.3. This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas.

Research Category :

Cancer, Cell Type Markers, Tags & Cell Markers, Tumor Antigens, Tumor Associated, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens

more info or order :

Boster product webpage