Mouse CD70/TNFSF7/cd27L ELISA Kit PicoKine® | Boster EK1310 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CD70/TNFSF7/cd27L ELISA Kit PicoKine®

catalog :

EK1310

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1310

Product Name :

Mouse CD70/TNFSF7/cd27L ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse CD70/TNFSF7/cd27L ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Cd70 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

CD70

Uniprot ID :

O55237

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S45-P195

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from rat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

CD70 antigen

Synonyms :

CD70 antigen;CD27 ligand;CD27-L;Tumor necrosis factor ligand superfamily member 7;CD70;Cd70;Cd27l, Cd27lg, Tnfsf7;

Protein Name :

CD70 antigen

Molecular Weight :

21919 MW

Protein Function :

Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Subcellular Localization :

Membrane; Single-pass type II membrane protein.

Tissue Specificity :

Very low level of expression. Detected in splenocytes and thymocytes.

Background :

CD70 (Cluster of Differentiation 70), also known as TNFSF7 or CD27L, is a ligand for CD27. This gene is mapped to 19p13.3. CD70 is a surface antigen found on activated, but not resting, T and B lymphocytes. It has been found that CD70 induced proliferation of costimulated T cells and enhanced generation of cytolytic T cells. CD70 is homologous to the ligands of the TNF receptor family, including TNF-alpha, TNF-beta, and the CD40 ligand, showing 19 to 24% amino acid sequence identity in the extracellular region.

Research Category :

Cancer, Cytokines, Growth Factors, Hematopoietic Progenitors, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Lymphocytic Lineage, Tnf Superfamily