Rat Angiopoietin-1 ELISA Kit PicoKine® | Boster EK1295 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat Angiopoietin-1 ELISA Kit PicoKine®

catalog :

EK1295

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Yuan Z, Zhao J, Shen J. [The changes of the ratio of angiopoietin-2 to angiopoietin-1 in the acute lung injury induced by phosgene in rats]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011;29:608-10 pubmed

image

image 1 :

Rat Angiopoietin-1 PicoKine ELISA Kit standard curve

product information

SKU :

EK1295

Product Name :

Rat Angiopoietin-1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Rat Angiopoietin-1 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Angpt1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

ANGPT1

Uniprot ID :

O35460

Immunogen :

Expression system for standard: NS0; Immunogen sequence: H16-F498

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Angiopoietin-1

Synonyms :

Angiopoietin-1;ANG-1;Angpt1;

Protein Name :

Angiopoietin-1

Molecular Weight :

57461 MW

Protein Function :

Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.

Subcellular Localization :

Secreted.

Background :

Angiopoietin 1, also called ANG1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. This gene was mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

Research Category :

Growth Factors

more info or order :

Boster product webpage