Human DLL1 ELISA Kit PicoKine® | Boster EK1276 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human DLL1 ELISA Kit PicoKine®

catalog :

EK1276

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Li J, Jia Y, Jia Y, Lu J, Jing L, Peng T, et al. [Significance of soluble DLL1 in diagnosis of intracranial infectious diseases in children]. Zhongguo Dang Dai Er Ke Za Zhi. 2011;13:205-7 pubmed

image

image 1 :

Human DLL1 PicoKine ELISA Kit standard curve

product information

SKU :

EK1276

Product Name :

Human DLL1 ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human DLL1 ELISA Kit PicoKine® (96 Tests). Quantitate Human DLL1 in cell culture supernatants, serum, plasma (heparin, EDTA) , urine and human milk. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

DLL1

Uniprot ID :

O00548

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S22-G540

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

78 pg/ml - 5,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA), urine and human milk

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Delta-like protein 1

Synonyms :

Delta-like protein 1;Drosophila Delta homolog 1;Delta1;H-Delta-1;DLL1;UNQ146/PRO172;

Protein Name :

Delta-like protein 1

Molecular Weight :

78056 MW

Protein Function :

Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Sequence Similarities :

Contains 1 DSL domain.

Background :

DLL1 (DELTA-LIKE 1), also known as DL1 or DELTA1, is a protein that in humans is encoded by the DLL1 gene. DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis, and it is also important in cell-to-cell communication. This gene is mapped to chromosome 6q27, near a locus for type I diabetes. Functional analysis suggested that a soluble fusion protein containing the DSL domain of DLL1 and its adjacent 50 N-terminal amino acids increased the viability of hemopoietic cells but inhibited cell death. It has been found that DLL1 blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

Research Category :

Developmental Biology, Embryogenesis, Embryonic Stem Cells, Epigenetics and Nuclear Signaling, Hematopoietic Progenitors, Intracellular, Neurogenesis, Neurology Process, Neuroscience, Signaling Pathways, Stem Cells, Surface Molecules, Transcription

more info or order :

Boster product webpage