Mouse Lumican ELISA Kit PicoKine® | Boster EK1261 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse Lumican ELISA Kit PicoKine®

catalog :

EK1261

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1261

Product Name :

Mouse Lumican ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Mouse Lumican ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Lum in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

LUM

Uniprot ID :

P51885

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q19-N338

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Lumican

Synonyms :

Lumican;Keratan sulfate proteoglycan lumican;KSPG lumican;Lum;Lcn, Ldc;

Protein Name :

Lumican

Molecular Weight :

38265 MW

Subcellular Localization :

Secreted, extracellular space, extracellular matrix .

Tissue Specificity :

Cornea and other tissues.

Sequence Similarities :

Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.

Background :

Lumican, also known as LUM, is a protein which in humans is encoded by the LUM gene. This gene is a member of the small interstitial proteoglycan gene (SIPG) family, and it is a keratan sulfate proteoglycan which presents large quantities in the corneal stroma and in interstitial collagenous matrices of the heart, aorta, skeletal muscle, skin, and intervertebral discs. Lumican is mapped to 12q21.33, it interacts with collagen and limits growth of fibrils in diameter. In the cornea, Lumican not only interacts with collagen molecules to limit fibril growth, but also plays a critical role in the regular spacing of fibrils and acquisition of corneal transparency by virtue of its keratan sulfate-containing glycosaminoglycan side chains LDC.

Research Category :

Cancer, Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction