Human Tetranectin/CLEC3B ELISA Kit PicoKine® | Boster EK1253 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Tetranectin/CLEC3B ELISA Kit PicoKine®

catalog :

EK1253

quantity :

96 wells/kit, with removable strips.

product information

SKU :

EK1253

Product Name :

Human Tetranectin/CLEC3B ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Description :

Human Tetranectin/CLEC3B ELISA Kit PicoKine® (96 Tests). Quantitate Human CLEC3B in cell culture supernatants and serum. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CLEC3B

Uniprot ID :

P05452

Immunogen :

Expression system for standard: NS0; Immunogen sequence: E22-V202

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

312 pg/ml - 20,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

polyclonal antibody from sheep, polyclonal antibody from sheep

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Tetranectin

Synonyms :

Tetranectin;TN;C-type lectin domain family 3 member B;Plasminogen kringle 4-binding protein;CLEC3B;TNA;

Protein Name :

Tetranectin

Molecular Weight :

22537 MW

Protein Function :

Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.

Subcellular Localization :

Secreted.

Tissue Specificity :

Found in plasma.

Sequence Similarities :

Contains 1 C-type lectin domain.

Background :

Tetranectin, also called TNA, is a protein that in humans is encoded by the CLEC3B gene. It is mapped to 3p21.31. Tetranectin, a tetrameric protein isolated from human plasma, has 4 identical and noncovalently bound polypeptide chains, each of 181 amino acid residues. It has a specific binding affinity for sulfated polysaccharides and the kringle 4 of plasminogen. The plasma concentration of tetranectin is reduced in patients with various malignancies. Tetranectin is a plasminogen-binding protein that is induced during the mineralization phase of osteogenesis. Thus, tetranectin is a candidate gene for human disorders affecting bone and connective tissue.

Research Category :

Cardiovascular, Cytoskeleton / Ecm, Extracellular Matrix, Serum Proteins, Signal Transduction, Structures