Human SPINK1/TATI ELISA Kit PicoKine® | Boster EK1241 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human SPINK1/TATI ELISA Kit PicoKine®

catalog :

EK1241

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Kemik O, Kemik A, Sumer A, Almali N, Gürlüler E, Gureş N, et al. The relationship between serum tumor-associated trypsin inhibitor levels and clinicopathological parameters in patients with gastric cancer. Eur Rev Med Pharmacol Sci. 2013;17:2923-8 pubmed

image

image 1 :

Human SPINK1/TATI PicoKine ELISA Kit standard curve

product information

SKU :

EK1241

Product Name :

Human SPINK1/TATI ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human SPINK1/TATI ELISA Kit PicoKine® (96 Tests). Quantitate Human SPINK1 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

SPINK1

Uniprot ID :

P00995

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: D24-C79

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Pancreatic secretory trypsin inhibitor

Synonyms :

Pancreatic secretory trypsin inhibitor;Serine protease inhibitor Kazal-type 1;Tumor-associated trypsin inhibitor;TATI;SPINK1;PSTI;

Protein Name :

Pancreatic secretory trypsin inhibitor

Molecular Weight :

8507 MW

Protein Function :

This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.

Subcellular Localization :

Secreted.

Background :

Serine protease inhibitor Kazal-type 1, also called TATI or PSTI, is a protein that in humans is encoded by the SPINK1 gene. It is mapped to 5q32. SPINK1 gene contains 4 exons spanning approximately 7.5 kb. It was initially detected in urine of patients with ovarian cancer. This peptide is also produced by the mucosa of the gastrointestinal tract where it may protect the mucosal cells from proteolytic breakdown. The SPINK1 gene encodes pancreatic secretory trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. Its physiologic role was thought to be the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.

Research Category :

Cell Biology, Protease Inhibitors, Proteolysis / Ubiquitin

more info or order :

Boster product webpage