Human TFF3/ITF ELISA Kit PicoKine® | Boster EK1234 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TFF3/ITF ELISA Kit PicoKine®

catalog :

EK1234

quantity :

96 wells/kit, with removable strips.

price :

369 USD

more info or order :

Boster product webpage

citations: 1

Reference
Xiao L, Liu Y, Xiao C, Ren J, Guleng B. Serum TFF3 may be a pharamcodynamic marker of responses to chemotherapy in gastrointestinal cancers. BMC Clin Pathol. 2014;14:26 pubmed publisher

image

image 1 :

Human TFF3 PicoKine ELISA Kit standard curve

product information

SKU :

EK1234

Product Name :

Human TFF3/ITF ELISA Kit PicoKine®

Size :

96 wells/kit, with removable strips.

Price :

369 USD

Description :

Human TFF3/Itf ELISA Kit PicoKine® (96 Tests). Quantitate Human TFF3 in cell culture supernatants, serum, plasma (heparin, EDTA) , saliva and urine. Sensitivity: 10pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

TFF3

Uniprot ID :

Q07654

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: E22-Y80

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA), saliva and urine

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from sheep

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Trefoil factor 3

Synonyms :

Trefoil factor 3;Intestinal trefoil factor;hITF;Polypeptide P1.B;hP1.B;TFF3;ITF, TFI;

Protein Name :

Trefoil factor 3

Molecular Weight :

8641 MW

Protein Function :

Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).

Subcellular Localization :

Secreted, extracellular space, extracellular matrix . Cytoplasm .

Tissue Specificity :

Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level).

Sequence Similarities :

Contains 1 P-type (trefoil) domain.

Background :

Trefoil factor 3 is a protein that in humans is encoded by the TFF3 gene. It is mapped to 21q22.3. Members of the trefoil family can interact with mucins and have an influence on mucus viscosity. They also promote migration of epithelial cells, are linked to antiapoptosis, induce cell scattering, trigger chemotaxis, and participate in immune responses. This gene is a marker of columnar epithelium and is expressed in a variety of tissues including goblet cells of the intestines and colon. It has been found that TFF3 is the most highly upregulated gene in 19 poorly differentiated endometrioid endometrial carcinomas (G3-EECs) compared with normal endometrium biopsies.

Research Category :

Cytoskeleton / Ecm, Ecm Proteins, Extracellular Matrix, Signal Transduction

more info or order :

Boster product webpage